| Country | Time | Match | Home | Away | Tip | Result |
| ESP | 2021-02-13 |
Celta Vigo
VS Elche |
Celta Vigo | Elche | 1X | (3:1) |
| GER | 2021-02-13 |
RB Leipzig
VS FC Augsburg |
RB Leipzig | FC Augsburg | W1 | (2:1) |
| AUT | 2021-02-13 |
Liefering
VS Austria Lustenau |
Liefering | Austria Lustenau | TO (1.5) | (3:1) |
| GER | 2021-02-13 |
Holstein Kiel
VS Würzburger Kickers |
Holstein Kiel | Würzburger Kickers | 1X | (1:0) |
| CZE | 2021-02-13 |
Slovácko
VS Teplice |
Slovácko | Teplice | 1X | (1:0) |
| ENG | 2021-02-12 |
Barnsley
VS Chelsea |
Barnsley | Chelsea | W2 | (0:1) |
| DEN | 2021-02-12 |
Vejle
VS Randers FC |
Vejle | Randers FC | 2X | (0:0) |
| AZ | 2021-02-12 |
FC Bayern Munich
VS Tigres UANL |
FC Bayern Munich | Tigres UANL | W1 | (1:0) |
| FRA | 2021-02-11 |
Caen
VS Paris Saint German |
Caen | Paris Saint German | W2 | (0:1) |
| BEL | 2021-02-11 |
Club Brugge
VS Royal Antwerp FC |
Club Brugge | Royal Antwerp FC | 1X | (3:1) |
| SUI | 2021-02-11 |
Young Boys
VS Lausanne |
Young Boys | Lausanne | W1 | (1:0) |
| AUT | 2021-02-11 |
Red Bull Salzburg
VS Austria Vienna |
Red Bull Salzburg | Austria Vienna | 1X | (3:1) |
| NED | 2021-02-11 |
Ajax Amsterdam
VS PSV Eindhoven |
Ajax Amsterdam | PSV Eindhoven | TO (2.5) | (2:1) |
| ENG | 2021-02-11 |
Swansea
VS Manchester City |
Swansea | Manchester City | W2 | (1:3) |
| GRE | 2021-02-11 |
PAOK
VS Lamia |
PAOK | Lamia | W1 | (5:2) |
| POR | 2021-02-10 |
Gil Vicente
VS Sporting |
Gil Vicente | Sporting | 2X | (1:2) |
| FRA | 2021-02-10 |
Lyon
VS Ajaccio |
Lyon | Ajaccio | W1 | (5:1) |
| ITA | 2021-02-10 |
Empoli
VS Pescara |
Empoli | Pescara | 1X | (2:2) |
| AUT | 2021-02-10 |
Sturm Graz
VS Ried |
Sturm Graz | Ried | 1X | (2:1) |
| ESP | 2021-02-09 |
Atlético Madrid
VS Celta Vigo |
Atlético Madrid | Celta Vigo | 1X | (2:2) |