| Country | Time | Match | Home | Away | Tip | Result |
| CZE | 2021-01-17 |
Slavia Praha
VS Sigma Olomouc |
Slavia Praha | Sigma Olomouc | W1 | (3:1) |
| NED | 2021-01-17 |
FC Emmen
VS Vitesse Arnhem |
FC Emmen | Vitesse Arnhem | 2X | (1:4) |
| CYP | 2021-01-16 |
Omonia Nicosia
VS Ethnikos Achnas |
Omonia Nicosia | Ethnikos Achnas | W1 | (2:0) |
| POR | 2021-01-16 |
Sporting
VS Rio Ave |
Sporting | Rio Ave | 1X | (1:1) |
| ROU | 2021-01-16 |
FCSB
VS Astra |
FCSB | Astra | 1X | (3:0) |
| GER | 2021-01-16 |
SpVgg Greuther Fürth
VS SC Paderborn 07 |
SpVgg Greuther Fürth | SC Paderborn 07 | 1X | (1:1) |
| BAN | 2021-01-15 |
Sheikh Russel
VS Brothers Union |
Sheikh Russel | Brothers Union | W1 | (2:1) |
| UAE | 2021-01-15 |
Hatta
VS Al Ain |
Hatta | Al Ain | 2X | (0:1) |
| ITA | 2021-01-15 |
Atalanta
VS Cagliari |
Atalanta | Cagliari | W1 | (3:1) |
| ENG | 2021-01-15 |
Arsenal
VS Crystal palace |
Arsenal | Crystal palace | 1X | (0:0) |
| NED | 2021-01-15 |
Willem II
VS FC Groningen |
Willem II | FC Groningen | 2X | (2:3) |
| NED | 2021-01-15 |
FC Twente
VS Ajax Amsterdam |
FC Twente | Ajax Amsterdam | TO (2.5) | (1:3) |
| GRE | 2021-01-15 |
Atromitos
VS Lamia |
Atromitos | Lamia | 1X | (2:1) |
| NED | 2021-01-14 |
Feyenoord
VS PEC Zwolle |
Feyenoord | PEC Zwolle | W1 | (1:0) |
| ENG | 2021-01-14 |
Manchester City
VS Brighton & Hove Albion |
Manchester City | Brighton & Hove Albion | W1 | (1:0) |
| POR | 2021-01-14 |
Braga
VS Torreense |
Braga | Torreense | W1 | (5:0) |
| POR | 2021-01-13 |
CF Estrela
VS Benfica |
CF Estrela | Benfica | W2 | (0:4) |
| ESP | 2021-01-13 |
Atlético Madrid
VS Sevilla |
Atlético Madrid | Sevilla | TU (3.5) | (2:0) |
| ENG | 2021-01-13 |
Burnley
VS Manchester United |
Burnley | Manchester United | 2X | (0:1) |
| GER | 2021-01-13 |
Bayer 04 Leverkusen
VS Eintracht Frankfurt |
Bayer 04 Leverkusen | Eintracht Frankfurt | BTS | (3:1) |